Substance

Tolvaptan

Brand name:
Samsca

Description

 
Aquaretic
 
The drug is prescribed to regulate sodium metabolism in patients with liver cirrhosis
Brands:
Samsca
Availability:
Prescription needed
Pregnancy:
Consult a doctor
Alcohol:
Doctors prohibit the intake of alcohol
Side Effects:
Confusion, Sweating, Rash
Interactions:
Avonex (interferon Beta-1a), Methotrexate, Amlodipine / Benazepril
For informational purposes only. Consult your local medical authority for advice.

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Important Information

You will need to be in a hospital under observation any time you start or restart treatment with tolvaptan.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Tell your caregivers at once if you have signs that your hyponatremia is being reversed too quickly: problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, confusion, or seizure.
While taking tolvaptan at home, call your doctor if you have signs of liver problems, such as: loss of appetite, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

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Changes We Want To See

CampaignTShirtOverhaul Cancer Drug Development

We are campaigning for the UK Government to tackle failures in the system for developing cancer drugs that have led to:
  • profiteering - a failure to curb excessive profit margins on drug prices, leading to drugs being priced out of reach of patients;
  • missed opportunities - a failure to attract investment in promising discoveries with limited commercial potential, or to provide alternative public funding;
  • ineffective drugs - a failure to reward development of drugs with greater therapeutic benefit, in order to speed up progress.
All of these issues have arisen due to the conflicting needs of the pharmaceutical industry, which we rely on to develop cures, and the patients who need them - put simply, wealth vs health.

We are calling on the UK Government to:
  • acknowledge the conflicting goals of those developing cancer drugs and those who need them
  • better regulate the pharmaceutical industry to protect cancer patients' interests
  • ensure that cancer drug prices reflect costs and the public contribution to their discovery
  • find ways to reduce the costs of bringing new cancer drugs to market to ease prices
  • publicly fund promising cancer treatments that fail to attract private investment
  • work with the World Health Organisation to consider alternative drug development models
  • to work with other countries to agree a goal and timeframe to cure the majority of cancers
Comments from Supporters
These are a selection comments from people supporting the campaign.  Help us tell those in Government that this is an issue that people care about, which is costing lives and causing unnecessary suffering: Sign the Petition Now
Christine Dunphy
Christine DunphyPetition
Get this changed Cameron. NOW!!!!!
Eva Roe
Eva RoePetition
A cure for cancer could be within our grasp if global reforms could be made so that countries research teams could work together.
Ann Abbott
Ann AbbottFacebook
Abuse of those of us who do what we can to support charities whose money funds the research that is supposed to help those suffering.
Susanna Williams
Susanna WilliamsPetition
I am despondent about the race for profits by the pharma industry in seeking new cancer breaking drugs. I also am getting cynical about the UK's cancer charities and ask myself what are they doing with the millions of pounds they attract each year?
Clive Nicholas
Clive NicholasPetition
The market is not sufficiently capable of rewarding cure or preventative treatments as well as life sustaining drugs.
Gloria Brady
Gloria BradyFacebook
It's a pity the EU don't get to grips with this serious situation instead of passing stupid laws on what we eat and what size it should be.
Robert Deakin
Robert DeakinPetition
Its totally immoral to make these drugs so unaffordable to the masses. I'm all for researchers and companies to make a good living from developing drugs to fight diseases like cancer, but how can you justify holding the NHS to ransom to purely make immensely, excessive profits? No justification at all.
Marina Billinge-Jones
Marina Billinge-JonesPetition
I feel this is blackmail. There is no justification for that abuse of power.
Wendy Neal
Wendy NealPetition
Its outrageous that cancer patients are suffering because of exorbitant prices of new drugs STOP IT NOW.
Louise Cartwright
Louise CartwrightPetition
You can't put a price on someone's life. A few extra years could mean that they could watch a child grow, get married, meet a grandchild, and lots more.
Yve Collins
Yve CollinsPetition
A cure needs to be found that is effective, not one created for profit.
Janine Gove
Janine GovePetition
There seem to have been many cancer breakthroughs in recent years, that have flared into a bright hope before fading away without ever becoming mainstream treatment. To learn that in treating seriously ill people, profit is put before innovation and progression, has left me appalled at the sheer waste of top notch research and the charity that funds it.
Wendy Harrison
Wendy HarrisonPetition
My son died of cancer at the age of 25. He was diagnosed with a rare sarcoma when he was 22. His chemo was so harsh but he endured it because he wanted to live, It is immoral to make such a huge profit at the cost of lives. It must be stopped.
Carole Core
Carole CorePetition
When we support cancer are doing just that - not for any other reason than to find cures and make our loved ones better.  Forget the profiteering that may be in involve - i's not for them we do it.
Allan Guest
Allan GuestFacebook
My mum lays in bed dying from cancer as i type this... Utterly f***ing disgusting!!!
Paul Donnachie
Paul DonnachiePetition
I object to rich companies using patent laws to rip off the sick and dying with high charges.
Cathy Gouge
Cathy GougeFacebook
Why are these companies allowed to make disgusting profits? Massive wealth should not be made through illness.
Jim Speed
Jim SpeedPetition
Yet another case of "rip off Britain" and the indifference of the good time over paid boys in parliament.
James Hobson
James HobsonPetition
I think it is diabolical, unfair and a damned disgrace to charge such overinflated prices for medication for people who are in need of this to save their lives. Companies charging such prices should be prosecuted as it's nothing short of robbery and fraud.
Louise Dickinson
Louise DickinsonPetition
I believe those who are profiteering from the sale of these drugs at over- inflated prices have blood on their hands, much the same as any murderer. They have the means to save lives but choose not to do so. Shame on them!
Sue Jones
Sue JonesFacebook
There aren't even enough words for people who profit from dying people and actually cause death because they only care about money. Beggars belief it's so shameful.
Danny Baverstock
Danny BaverstockPetition
Would the profiteers feel that the paper in their wallet meant anything if they themselves were at deaths door, dying from the very thing they once had the power to cure?
Carolyn Crawford
Carolyn CrawfordFacebook
Absolutely shocking. Lives don't matter anymore. Consciences have been desensitised in the name of greed.
Catherine Davis
Catherine DavisPetition
Make the industry back off. Stop this behaviour now. It is stealing our loved ones. Please I beg you with all of me to put a stop to this.
Lorraine Murphy
Lorraine MurphyPetition
My husband was forced to have chemotherapy which he didn't want in order to get the drug he needed, which cost a lot more - the chemotherapy didn't work.
Christine Elliot
Christine ElliotPetition
The pharmaceutical companies are putting profit before cure, basically lining their pockets at the expense of people's lives.
Lorna Cooke
Lorna CookeFacebook
This is disgusting the Government needs to make a stand!!
Avril Williams
Avril WilliamsFacebook
I lost my dad 20yrs ago and my brother 3 yrs ago and now I'm going through it makes me so sick its all about money.
Nina Scothern
Nina ScothernPetition
I watched my mother in law die a slow and painful death from ovarian cancer. I am disgusted with profits big pharma makes from the suffering of individuals
Dawn Woodhams
Dawn WoodhamsPetition
I have lost 3 immediate family members to cancer and to learn this makes me so mad...Total greed the scourge of our time now....

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